University of Kentucky College of Agriculture Agripedia
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Antisense

Antisense is the adjective indicating the DNA strand that is not normally transcribed or the RNA that is complementary to it; the DNA antisense strand is complementary to the DNA "sense" strand that is normally transcribed; an antisense RNA is complementary to the mRNA that is transcribed from the DNA "sense" strand.

To make this a little more understandable, an antisense DNA strand is not transcribed to make mRNA for translation into a protein.

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