Professional Experience
2005; Associate Professor of Virology, Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, Lexington
2001 - 2005; Associate Research Molecular Virologist, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis
1999 - 2005; Scientific Director and Coordinator, Equine Viral Disease Laboratory, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis
1997 - 2001; Assistant Research Molecular Virologist, Department
of Pathology, Microbiology and Immunology, School of Veterinary
Medicine, University of California, Davis
1996 -1997; Postdoctoral Fellow, Department of Pathology, Microbiology
and Immunology, School of Veterinary Medicine, University
of California, Davis
1991 - 1996; Graduate Student/Postgraduate Researcher, Department
of Pathology, Microbiology and Immunology, School of Veterinary
Medicine, University of California, Davis
1990 - 1992; Residency training in Diagnostic Veterinary
Pathology, Veterinary Medical Teaching Hospital, University
of California, Davis.
1989 - 1991; Graduate Student, Department of Pathology, School
of Veterinary Medicine, University of California, Davis.
1985 - 1989; Veterinary Research Officer, Veterinary Research
Institute, Sri Lanka.
Peer-Reviewed Publications (2006-2008)
Balasuriya, U. B. R., Shi, P. –Y., Wong, S. J., Demarest, V. L., Gardner, I. A., Hullinger, P. J. Ferraro, G. L., Boone, J. D., De Cino, C. L., Glaser, A. L., Renshaw, R. W., Ledizet, M., Koski, R. A., and MacLachlan, N. J. 2006. Detection of antibodies to West Nile virus in equine sera using microsphere immunoassay, J. Vet. Diagn. Invest. 18:392-95.
Bell, S. A., Balasuriya, U. B. R., Gardner, I. A., Barry, P. A., Wilson, W. D., Ferraro, G. L., and MacLachlan, N. J. 2006. Temporal detection of equine herpesvirus infections of a cohort of mares and their foals. Vet. Microbiol. 116(4):249-57.
Bell, S. A., Balasuriya, U. B. R., and MacLachlan, N. J. 2006. Equine viral arteritis. Clinical Techniques in Equine Practice 5(3):233-8.
Bell, S. A., Balasuriya, U. B. R., Nordhausen, R. W., and MacLachlan, N. J. 2006. Isolation of equine herpesvirus–5 from blood mononuclear cells of a California gelding. J. Vet. Diagn. Invest. 18(5):472-5.
Gardner, I.A., Wong, S. J., Ferraro, G. L., Balasuriya, U. B. R., Hullinger P. J., Wilson W. D., Shi, P. –Y., MacLachlan, N. J. 2007. Incidence and effects of West Nile virus infection in vaccinated and unvaccinated horses in California. Vet Res 38(1):109-16.
Boone, J. D., Balasuriya, U. B. R., Karaca, K., Audonnet, J. –C., Yao, J., He, L., Nordgren, R., Monaco, F., Savini, G., Gardner, I. A., and MacLachlan, N. J. 2007. Recombinant canarypox virus vaccine co-expressing genes encoding the VP2 and VP5 outer capsid proteins of bluetongue virus induces high-level protection in sheep. Vaccine 25(4):672-8.
Balasuriya, U. B. R., Snijder, E. J., Heidner, H. W., Zhang, J., Zevenhoven-Dobbe, C., Boone, J. D., Zhang, J., McCollum, W. H., Timoney, P. J., and MacLachlan, N. J. 2007. Development and characterization of an infectious cDNA clone of the virulent Bucyrus strain of equine arteritis virus J. Gen. Virol. 88:918-24.
MacLachlan, N. J., Balasuriya, U. B. R., Davis, N. L., Collier, M., Johnston R. E., and Guthrie, A. J. 2007. Experiences with new generation vaccines against equine viral arteritis, West Nile disease and African horse sickness. Vaccine 25(30):5577-82.
Hallam K. M., Edirisinghe, I., Balasuriya, U. B. R., Gunawardena, S., Bravo, E. M., Ravi, K., and Kappagoda, C. T. 2007. Effects of mitral regurgitation on the reflex diuresis to pulmonary lymphatic obstruction in rabbits. Exp. Lung Res. 33(5):259-75.
Zhang, J., Miszczak, F., Pronost, S., Fortier, C., Balasuriya, U. B. R., Zientara, S., Fortier, G., and Timoney, P. J. 2007. Genetic variation and phylogenetic analysis of 22 French Strains of equine arteritis virus. Arch. Virol. 152(11):1977-94.
Zhang J. Q., Guy, J. S., Snijder, E. J., Denniston, D. A., Timoney, P. J., and Balasuriya, U. B. R. 2007. Genomic characterization of equine coronavirus. Virology 369(1):92-104.
MacLachlan, N. J., Zientara, S., Stallknecht, D. E., Boone, J. D., Goekjian, V. H., Sailleau, C., and Balasuriya, U. B. R. 2007. Phylogenetic comparison of the S10 genes of recent isolates of bluetongue virus from the United States and French Martinique Island. Virus Res. 129(2):236-40.
Balasuriya, U. B. R., Nadler, S. A. Wilson, W. C. Pritchard, L. I., Smythe, A. B., Savini, G., Monaco, F., De Santis, P., Zhang, N., Tabachnick, W. J. and MacLachlan, N. J. 2008. The NS3 proteins of global strains of bluetongue virus evolve into regional topotypes through negative (purifying) selection. Vet Microbiol. 126(1-3):91-100.
Go, Y. Y., Wong, S. J., Branscum, J. A., Demarest, V. L., Shuck, K. M., Vickers, M. L., Zhang, J., McCollum, W. H., Timoney, P. J., and Balasuriya, U. B. R. 2008. Development of a fluorescent microsphere immunoassay for detection of antibodies specific to equine arteritis virus and comparison with the virus neutralization test. Clin Vaccine Immunol. 15(1):76-87.
Lu, Z., Branscum, J. A., Shuck, K. M., Zhang, J., Dubovi, E., Timoney, P. J., and Balasuriya, U. B. R. 2008. Comparison of two real-time reverse transcription polymerase chain reaction assays for the detection of equine arteritis virus nucleic acid in equine semen and tissue culture fluid. J. Vet. Diagn. Invest. 20(2):147-55.
Bell, S. A., Pusterla, N., Balasuriya, U. B. R., Mapes, S. M., Nyberg, N. L., and MacLachlan, N. J. 2008. Isolation of a gammaherpesvirus similar to asinine herpesvirus-2 (AHV-2) from a mule and a survey of mules and donkeys for AHV-2 infection by real-time PCR. Veterinary Microbiol. 130(1-2):176-83.
Holyoak G. R., Balasuriya U. B., Broaddus C. C., Timoney P. J. 2008. Equine viral arteritis: Current status and prevention. Theriogenology 70(3):403-14.
Zhang J., Go Y.Y., Maclachlan N.J., Meade B. J., Timoney P. J., Balasuriya U. B. R. 2008. Amino acid substitutions in the structural or nonstructural proteins of a vaccine strain of equine arteritis virus are associated with its attenuation. Virology [2008 July 9, Epub ahead of print; PMID: 18619638].
Zhang J., Timoney P. J., Maclachlan N. J., McCollum W. H., Balasuriya U. B. 2008. Persistent equine arteritis virus infection in HeLa cells. J Virol. [2008 June 25, Epub ahead of print, PMID: 18579588].
Zhang, J., Timoney, P. J., MacLachlan, N. J., Balasuriya, U. B. R. 2008. Identification of an additional neutralization determinant of equine arteritis virus. Virus Res. (Submitted).
Book Chapters
Balasuriya, U. B. R., Hedges, J. F., and MacLachlan, N. J. 2001. Molecular epidemiology and evolution of equine arteritis virus. In: Advances in Experimental Biology (The Nidoviruses), Edited by E. Lavi et al. Kluwer Academic/Plenum Publishers. pp. 19-23.
Hedges, J. F., Balasuriya, U. B. R., Topol, J.B., Lee, D. W. and MacLachlan, N. J. 2001. Genetic variation of ORF3 and 4 of equine arteritis virus. In: Advances in Experimental Biology (The Nidoviruses), Edited by E. Lavi et al. Kluwer Academic/Plenum Publishers. pp. 69-72.
Balasuriya, U. B. R., and Stott, J. L. 2004. Coronaviridae and Arteriviridae. In: Veterinary Microbiology (Second edition), Edited by D. C. Hirsh et al., Blackwell Publishing, Ames, IA. pp. 383-397.
MacLachlan, N. J., and Balasuriya, U.B. R. 2006. Equine viral arteritis. In: Advances in Experimental Biology, volume 581, (Proceeding of the Xth Nidoviruses Symposium). Edited by S. Perlman, Kluwer Academic/Plenum Publishers. pp 429-433.
Balasuriya, U. B. R., and MacLachlan, N. J. 2007. Equine viral arteritis. In: Infectious Diseases of the Horse. Edited by Debra Sellon and Maureen Long, Saunders Elsevier, Chapter 14, pp 153-164.
MacLachlan, N. J., and Balasuriya, U.B. R., Murtaugh, M. P., Barthold, S. W., and Lowenstine, L. J. 2007. Arterivirus pathogenesis and immune response. In: Nidoviruses. Edited by S. Perlman, American Society of Microbiology Press, Chapter 21.
Balasuriya, U. B. R., and Snijder, E. J. 2007. Arteriviruses. In: Animal Viruses: Molecular Biology. Edited by Thomas C. Mettenleiter and Francisco Sobrino, Caister Academic Press, Chapter 3, pp 97-148.
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