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Gluck Center > Research > Gluck Equine Research Center > Immunology > Equine Immunology Resource Page > Cloned Equine Cytokines

Cloned Equine Cytokines
The information contained in this table is deemed accurate, but no warranty is expressed or implied.
Additions or corrections to this table may be sent to Dr. David Horohov, David.Horohov@uky.edu.

Move mouse over Cytokine name for more information. Move mouse over Order Name for figure and click for larger version.
Cytokine* GeneBank Accession Reference RT-PCR**
ABI # Order Name
IL-1α D42146, E13117,U92480 (Howard et al., 1997; Howard et al., 1998; Kato, 1994;
Kato et al., 1995; Katou et al., 1997; Takafuji et al., 2002)
IL-1β D42147, D42165, E13118, U92481 (Howard et al., 1997; Howard et al., 1998; Kato, 1994;
Kato et al., 1995; Kato et al., 1996; Katou et al., 1997;
Takafuji et al., 2002)
 1749300 EQIL-1B-JN2
IL-1ra U92482, D83714 (Howard et al., 1997; Howard et al., 1998;
Kato, 1996; Kato et al., 1997)
IL-2 L06009, X69393 (Dohmann et al., 2000; Tavernor, 1992;
Tavernor, 1993; Vandergrifft and Horohov, 1993)
 1918058 EquineIL-2-JN2
IL-4 L06010, AF035404, AF305617 (Hammond et al., 1999; Dohmann et al., 2000;
Schrenzel et al., 1997; Schrenzel et al., 2001;
Steinbach and Mauel, 2000; Vandergrifft et al., 1994)
 1798106 EQIL4IS-JN2
IL-5 U91947 (Cunningham et al., 2003; Vandergrifft and Horohov, 1997) 50442836 EQIL5IS-JN1
IL-6 U64794, AF005227, AF041975 (Lai, 1998; Leutenegger et al., 1997;
Swiderski and Horohov, 1996; Swiderski et al., 2000)
 50414323 EQIL-6
IL-8 AF062377, AY184956 (Capelli et al., 2002; Franchini, 1998;
Nergadze et al., 2006)		 1833786 EQIL-8IS-JN1
IL-10 U38200 (Swiderski et al., 1995) 50442836 EQIL10IS-JN2
IL-12p35 Y11130 (McMonagle et al., 2001; Nicolson, 1997;
Nicolson et al., 1999)
IL-12p40 Y11129 (McMonagle et al., 2001; Nicolson, 1997;
Nicolson et al., 1999)		 1649196 IL-12
IL-13 DQ889711 50442836 EQIL13IS-JN1
IL-15 AY682849 (Cook et al., 2004) 1833786 EQIL-15IS-JN1
IL-17 AY014959 (Joubert et al., 2000)
IL-18 Y11131 (Nicolson, 1997; Nicolson et al., 1999) 1833786 EQIL-18IS-JN3
IL-23 AY704416 (Kralik, 2004; Kralik et al., 2006; Musilova et al., 2005)
GM-CSF AY040203, AF448481 (Mauel et al., 2001; Mauel et al., 2006;
Vecchione et al., 2001; Vecchione et al., 2002)
IFN-α 1 M14540 (Himmler et al., 1986; Steinbach et al., 2002) 1947516 EQIFNA-4-SITER
IFN-α 2 M14541 (Himmler et al., 1986; Steinbach et al., 2002)
IFN-α 3 M14542 (Himmler et al., 1986; Steinbach et al., 2002)
IFN-α 4 M14543 (Himmler et al., 1986; Steinbach et al., 2002)
IFN-β M14546 (Adolf et al., 1990; Himmler et al., 1986;
Steinbach et al., 2002)
 1947516 EQIFNBETA-SITER
IFN-γ M14544, D28520, U04050 (Curran et al., 1994; Grunig, 1993; Grunig et al., 1994;
Himmler et al., 1986; Nicholson, 1994; Steinbach et al., 2002)
 50442836 EQIFNGIS-JN3
TGF-β X99438, AF175709 (Nixon et al., 1999; Penha-Goncalves, 1996;
Penha-Goncalves et al., 1997)
TNF-α M64087 (Su et al., 1991; Su et al., 1992) 1787254 EQTNFAIS-JN2


*Coligan, John E.; Ada M. Kruisbeek; David H. Margulies; Ethan M. Shevach; and Warren Strober (eds.). Current Protocols in Immunology. September, 2004.

**RT-PCR: Real-Time PCR Primers and Probes available as Assay-by-Design kits from Applied Biosystems (ABI). Each intron-spanning primer/probe combination amplifies cDNA but not chromosomal DNA with the exception of IFN-α and IFN-β, which lack introns (see figures).

 

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