Education
Purdue University (W. Lafayette, IN); Ph.D.: Molecular Parasitology,
December 1992
Western Illinois University (Macomb, IL); M.S.: Biology/Parasitology,
July 1990
Western Illinois University (Macomb, IL); B.S.: Biology,
May 1988
Appointments and Professional Experience
07/05-Present; Associate Professor, Department of Veterinary
Science, M.H. Gluck Equine Research Center, University of
Kentucky, Lexington, KY.
07/99-06/05; Assistant Professor, Department of Veterinary
Science, M.H. Gluck Equine Research Center, University of
Kentucky, Lexington, KY.
01/93-06/99; Postdoctoral Research Associate, Department
of Molecular Microbiology, Washington University School of
Medicine, St. Louis, MO.
08/90-12/92; Graduate Research Assistant, Department of
Veterinary Pathobiology, University of Illinois, Urbana,
IL, August, 1990-August, 1991; Department of Veterinary Pathobiology,
Purdue University, W. Lafayette, IN, September, 1991-December,
1992.
1988-1990; Graduate Teaching Assistant, Department of Biology,
Western Illinois University, Macomb, IL.
1989-1990; Laboratory Instructor, Spoon River College, Macomb,
IL.
Recent Honors/Awards
Recipient of the Amerman Family Equine Research Endowment,
2004-present.
University of Kentucky Faculty Futures Award, 2004.
Patents
U.S. patents 7,056,733, and 7,256,282 “Nucleic acids encoding Sarcocystis neurona antigens and uses thereof.” Daniel K. Howe, inventor.
U.S. patent application #09/767,037 “Immunological detection of neosporosis using a recombinant antigen.” L.D. Sibley and D.K. Howe, co-inventors.
Selected Publications (of 46)
Howe, D.K. 2001. Initiation of a Sarcocystis neurona merozoite expressed sequence tag (EST) sequencing project: a preliminary report. Veterinary Parasitology 95:233-240.
Su, C., D.K. Howe, J.P. Dubey, J. Ajioka, and L.D. Sibley. 2002. Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii. Proceedings of the National Academy of Sciences 99:10753-10758.
Li, L., B. Brunck, J. Kissinger, D. Pape, K. Tang, R. Cole, J. Martin, T. Wylie, M. Dante, S.J. Fogarty, D.K. Howe, P. Liberator, C. Diaz, J. Anderson, M. White, M.E. Jerome, E.A. Johnson, J.A. Radke, C.J. Stoeckert, Jr., R.H. Waterston, S.W. Clifton, D.S. Roos, and L.D. Sibley. 2003. Gene discovery in the Apicomplexa as revealed by EST sequencing and assembly of a comparative gene database. Genome Research 13:443-454.
Hoane, J.S., V.B. Carruthers, B. Striepen, R. Entzeroth, and D.K. Howe. 2003. Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development. International Journal for Parasitology 33:671-679.
Howe, D.K., R. Gaji, M. Mroz-Barrett, M-J. Gubbels, B. Striepen, and S. Stamper. 2005. Sarcocystis neurona merozoites express a family of immunogenic surface antigens that are orthologues of the SAG/SRS surface antigens in Toxoplasma gondii. Infection and Immunity 73(2):1023-1033.
Hoane, J.S., J.K. Morrow, W.J. Saville, J.P. Dubey, D.E. Granstrom, and D.K. Howe. 2005. Enzyme-linked immunosorbent assays for the detection of equine antibodies specific to Sarcocystis neurona surface antigens. Clinical and Diagnostic Laboratory Immunology 12(9):1050-1056.
Gaji, R.Y., D. Zhang, C. Breathnach, S. Vaishnava, B. Striepen, and D.K. Howe. 2006. Molecular genetic transfection of the coccidian parasite Sarcocystis neurona. Molecular and Biochemical Parasitology 150:1-9.
Zhang, D., R.Y. Gaji, and D.K. Howe. 2006. Identification of a dithiol-dependent nucleoside triphosphate hydrolase in Sarcocystis neurona. International Journal for Parasitology 36:1197-1204.
Herman, R.K., R. Molestina, A. Sinai, and D.K. Howe. 2007. The apicomplexan pathogen Neospora caninum inhibits host cell apoptosis in the absence of discernible NF-kB activation. Infection and Immunity 75(9):4255-4262. |
