Education
1997; University of Kentucky, Department of Veterinary
Science, Ph.D. (Genetics).
1986; University of Louisville, Department of Biology,
M.S. (Cytogenetics/Zoology).
1975; Indiana University Southeast, Department of Natural
Sciences, B.A. (Zoology/Field Biology).
Academic Positions
2005-present; Research Associate Professor, Molecular
Cytogenetics, Department of Veterinary Science, University
of Kentucky
1998-2005; Research Assistant Professor, Molecular Cytogenetics,
Department of Veterinary Science, University of Kentucky.
Selected Publications
Tallmadge RL, Lear TL, and Antczak DF (2005). Genomic
characterization of MHC class I genes of the horse. Journal
of Immunology (in press).
Perelygin AA, Lear TL, Zharkikh AA, Brinton MA (2005).
Structure of equine 2’-5’ oligoadenylate synthetase
gene family. Cytogenetic and Genome Research 111: 51-56.
Ward TL, Valberg SJ, Lear TL, Guerin G, Milenkovic D,
Swinburne J, Binns MM, Chowhary BP, Raudsepp T, Skow L,
Mickelson JR (2003). Genetic mapping of GBE1 and its association
with glycogen storage disease IV in American Quarter horses.
Cytogenetic and Genome Research 102:201-206.
Myka JL, Lear TL, Houck ML, Ryder OA, Bailey E (2003).
FISH analysis comparing genome organization in the domestic
horse (Equus caballus) to that of the Mongolian
Wild horse (E. przewalskii). Cytogenetic and Genome
Research 201:222-225.
Myka JL, Lear TL, Houck ML, Ryder OA, Bailey E (2003).
Homologous fission event(s) implicated for chromosomal
polymorphisms among 5 species in the genus Equus. Cytogenetic
and Genome Research 201:217-221.
Chowdhary BP, Raudsepp T, Kata SR, Goh G, Millon LV, Allan
V, Piumi F, Guerin G, Swinburne J, Binns M, Lear TL, Mickelson
J, Murray J, Antczak DF, Womack JE, Skow LC (2003). The
first generation whole genome radiation hybrid map in the
horse identifies conserved segments in human and mouse
genomes. Genome Research 13:742-751.
Milenkovic D, Oustry-Vaiman A, Lear TL, Billault A, Mariat
D, Piumi F, Schibler L, Cribiu E, Guerin G (2002). Cytogenetic
localization of 136 genes in the horse: comparative mapping
with the human genome. Mammalian Genome 13:524-534.
Raudsepp T, Lear TL, Chowdhary BP (2002). Comparative
mapping in equids: the asine X chromosome is rearranged
compared to horse and Hartmann’s mountain zebra.
Cytogenetics and Genome Research 96:206-209.
Lear TL, Layton G (2002). Use of Zoo-FISH to characterize
a reciprocal translocation in a Thoroughbred mare: t(1;16)(q16;q21.3).
Equine Veterinary Journal 43:207-209.
Lear TL, Houck M, Zhang YW, Debnar LA, Sutherland-Smith
MR, Young LA, Jones KL, Bernirschke K (2001). Trisomy 17
in a Bonobo (Pan paniscus) and deletion of 3q
in a Lowland Gorilla (Gorilla gorilla): comparison
with human trisomy 18 and human deletion 4q syndrome. Cytogenetics
and Cell Genetics 95: 228-233.
Lear TL (2001). Chromosomal distribution of the telomere
sequence (TTAGGG)n in the Equidae. Cytogenetics and Cell
Genetics 93:127-130.
Lear TL, Cox JH, Kennedy GA (1999). Autosomal Trisomy
in a Thoroughbred Colt:65,XY,+31. Equine Veterinary Journal
31: 85-88.
ISCNH (1997), International system for cytogenetic nomenclature
of the domestic horse. Bowling AT, Breen M, Chowdhary BP,
Hirota K, Lear TL, Millon LV, Ponce de Leon FA, Raudsepp
T, Stranzinger G, (Committee). Chromosome Research 5:443-453.
Selected Abstracts
Lear TL, Houck ML, Lundquist J, Fronczek J, Bailey E (2005).
Chromosome Evolution in Perissodactyls: Horse Chromosome
1.14th North American Colloquium on Animal Cytogenetics
and Gene Mapping, Puerto Vallarta, Mexico.
Bellone R, Lear TL, Durkin K, Adelson D, Bailey E (2005).
Fish Mapping Appaloosa candidate genes in the Horse. Havemeyer
International Horse Genome Workshop, Dublin, Ireland.
Brooks S, Lear TL, Adelson D, Murphy B, Bailey E (2005).
Inversion on ECA3 Associated with Tobiano Spotting Pattern.
Havemeyer International Horse Genome Workshop, Dublin,
Ireland.
Perrocheau M, Boutreux V, Chadi-Taourit S, Chowdhary BP,
Cribiu EP, de Jong PJ, Durkin K, Hasegawa T, Hirota K,
Ianuzzi L, Incarnato D, Lear TL, Raudsepp T, Percuatti
A, Pia Di Meo G, Zhu B, Guerin G (2005). Cytogenetic mapping
of 150 genes on the horse genome. Plant & Animal
Genome Conference XIII, San Diego, CA.
Lear TL (2005). Using horse gene mapping tools to study
chromosome evolution in Perissodactyls. Plant & Animal
Genome Conference XIII, San Diego, CA.
Lear TL, Houck ML, Lundquist JM, Fronczek JA, Ryder OA
(2005). Comparative gene mapping of endangered rhinoceros
species. Plant & Animal Genome XIII, San Diego, CA.
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