Gluck Center > Directory > Gluck Faculty >MacLeod, JN > Research Projects
RESEARCH PROJECTSEquine Gene Structure Annotation |
James N. MacLeod, VMD, PhD
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Welcome to the MacLeod Lab Equine Genome Browser. This resource was developed to support the analysis of protein-coding genes in the horse. Consensus structural annotation was generated by combining in silico predictions from Ensembl and NCBI with equine-specific data from RNA-sequencing (RNA-seq) experiments*. A majority of the consensus gene models are computationally generated, including exon boundaries defined by the RNA-seq read alignments. Annotation on only a subset of gene loci have been manually curated. As such, careful analysis of any specific locus of interest is recommended. The browser displays the consensus gene models, the supporting RNA-seq derived data (when available), and/or in silico Ensembl and NCBI predictions (when available). Searches can be performed using gene IDs (from Ensembl or NCBI), locus IDs, or specific genomic locations (chromosome #: start-stop). The server supporting this database is hosted by Intrepid Bioinformatics (http://www.intrepidbio.com/). |
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*Please use the following citation if information from this browser is included in a publication:SJ Coleman, Z Zeng, K Wang, S Luo, I Khrebtukova, MJ Mienaltowski, GP Schroth, J Liu, and JN MacLeod. (2010) Structural Annotation of Equine Protein-Coding Genes Determined by mRNA Sequencing. Animal Genetics 41(Supplement 2): 121-130. [PMID: 21070285] |
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Maxwell H.Gluck Equine Research Center
Department of Veterinary Science, University of Kentucky
Lexington, Kentucky 40546-0099
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