University of Kentucky College of Agriculture
Home
 
Academics
 
Extension
 
Research
 
People
 
Alumni-Careers
 
Employment
 
Seminars
 
Contact Us
 
News
 
Publications
 
Courses
 
JosephChappell

Joseph Chappell

Professor

Faculty

  • Contact Information
  • Directions to University of Kentucky, Lexington, KYUniversity of Kentucky, PSS
    Campus LocationPlant Science Building
    1405 Veterans Drive (Office:301B)
    Lexington, KY 40546-0312
    Phone(859) 257-5020 ext. 80775
    Fax(859) 257-7125
    Emailchappell@uky.edu

Classes

    Abt495 - Experimental Techniques in Biotechnology; Credits - 4
    A laboratory course designed to give students the technical skills and understanding necessary to critically examine biological systems at the molecular level. This course emphasizes the principles of chemistry, biochemistry and molecular biology as applied to a model system for laboratory investigations..
    Instructors: Joseph Chappell
    Pls601 - Special Topics in Molecular and Cellular Genetics; Credits - 1
    Each semester five distinguished scientists visit the UK campus to deliver a series of three formal lectures each and participate in numerous informal contacts with graduate students. The emphasis is on the presentation of the most current advances (often unpublished) in selected topics in molecular and cellular genetics. May be repeated to a maximum of six credits. (Same as BCH/BIO/MI/PPA 601.) .
    Instructors: Joseph Chappell

Research/Teaching Publications

    Refereed Journal Articles

    Deguerry, F., L. Pastore, S. Wu, J. Chappell, A. Clark, and M. Schalk. 2006. The diverse sesquiterpene profile of Patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases. Arch Biochem. Biophys. 454: 123-136.
    Authors in PSS Dept.: Joseph Chappell
    Greenhagen, B.T., P.E. O’Maille, J.P. Noel and J. Chappell. 2006. Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases. Proc. Natl. Acad. Sci. 103:9826-9831.
    Authors in PSS Dept.: Joseph Chappell
    O’Maille, P.E., J. Chappell, and J.P. Noel. 2006. Biosynthetic potential of sesquiterpene synthases: alternative products of tobacco 5-epi-aristolochene synthase. Arch. Biochem. Biophys. 448:73-82.
    Authors in PSS Dept.: Joseph Chappell
    Schenk, D.J., C.M. Starks, K.R. Manna, J. Chappell, J.P. Noel and R.M. Coates. 2006. Stereochemistry and deuterium isotope effects associated with the cyclization-rearrangements catalyzed by tobacco epiaristolochene and hyoscyamus premnaspirodiene synthases, and the chimeric CH4 hybrid cyclase. Arch. Biochem. Biophys. 448:31-44.
    Authors in PSS Dept.: Joseph Chappell
    Takahashi, S., Y. Yeo, B.T. Greenhagen, L. Song, J. Maurina-Brunker, R. Rosson, J.P. Noel and J Chappell. 2006. Metabolic engineering of sesquiterpene metabolism in yeast. Biotech. Bioeng. (in press, DOI 10.1002/bit. 21216).
    Authors in PSS Dept.: Joseph Chappell
    Wu, S., M. Schalk, A. Clark, R.B. Miles, R.M. Coates and J. Chappell. 2006. Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants. Nature Biotech. (in press).
    Authors in PSS Dept.: Joseph Chappell
    Xu, D., Y. Shen, J. Chappell, M. Cui and M. Nielsen. 2006. Biochemical and molecular characterization of nicotine demethylase in tobacco. Physiologia Plantarum (in press).
    Authors in PSS Dept.: Joseph Chappell
    Takahashi, S., Y. Zhao, P.E. O’Maille, B.T. Greenhagen, J.P. Noel, R.M. Coates, and J. Chappell. 2005. Kinetic and molecular analysis of 5-Epiaristolochene-1,3-Dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes. Journal of Biological Chemistry 280:3686-3696.
    Authors in PSS Dept.: Joseph Chappell
    Wu, S., M.A. Schoenbeck, B.T. Greenhagen, S. Takahashi, S. Lee, R.M. Coates, and J. Chappell. 2005. Surrogate splicing for functional analysis of sesquiterpene synthase genes. Plant Physiology 138:1322-1333.
    Authors in PSS Dept.: Joseph Chappell Shuiqin Wu
    Chappell, J. 2004. Valencene synthase—a biochemical magician and harbinger of transgenic aromas Trends Plant Science 9:266-269.
    Authors in PSS Dept.: Joseph Chappell
    Okada, S., T.P. Devarenne, M. Murakami, H. Abe, and J. Chappell. 2004. Characterization of botryococcene synthase enzyme activity, a squalene synthase-like activity from the green microalga Botryococcus braunii, Race B. Archives of Biochemistry and Biophysics 422: 110-8.
    Authors in PSS Dept.: Joseph Chappell
    O’Maille, P.E., J. Chappell, and J.P. Noel. 2004. A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases. Analytical Biochemistry 15:210-217.
    Authors in PSS Dept.: Joseph Chappell
    O’Maille, P.E., M.D. Tsai, B.T. Greenhagen, J. Chappell, and J.P. Noel. 2004. Gene library synthesis by structure-based combinatorial protein engineering. Methods in Enzymology 388:75-91.
    Authors in PSS Dept.: Joseph Chappell
    Zhao, Y., D.J. Schenk, S. Takahashi, J. Chappell, and R.M. Coates. 2004. Eremophilane sesquiterpene from capsidiol. Journal Organic Chemistry 9:7428-435.
    Authors in PSS Dept.: Joseph Chappell

This person page last updated on 2010-01-15