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Reference Standards, Internal Standards and Critical Reagents/Regulatory Analytes for Analytical/Toxicological Approaches to Problems in Equine Medicine
Department of Veterinary Sciences
1/ To identify, synthesize and make available to equine forensic chemists worldwide certified reference standards for unique urinary drug/metabolite fragments for therapeutic medication regulation.
2/ To synthesize and make available to equine forensic chemists worldwide deuterated or other stable isotope internal reference standards for the above unique urinary drug/metabolite fragment standards to allow accurate forensic quantification.
3/ To identify and synthesize certified reference standards and stable isotope internal standards for glucuronide metabolites of high potency therapeutic medications.
4/ To develop cost-effective methods of synthesizing ergovaline and related ergot alkaloids and haptens of same with the goal of creating highly sensitive and specific ELISA tests for these substances.
5/ To complete ongoing work on establishing the therapeutic efficacy of diclazuril in the therapy and prophylaxis of certain Toxoplasma related syndromes.